The Constant Gardener
by John le Carre
Justin Quayle, a British diplomat in Nairobi, Kenya, is told that his activist wife, Tessa, was killed while travelling with a doctor friend in a desolate region of Africa. Investigating on his own, Quayle discovers that her murder, reportedly committed by her friend, may have had more sinister roots.
Justin learns that Tessa had uncovered a corporate scandal involving medical experimentation in Africa. KVH (Karel Vita Hudson), a large pharmaceutical company working under the cover of AIDS tests and treatments, is testing a tuberculosis drug that has severe side effects. Rather than help the trial subjects and begin again with a new drug, KVH covered up the side effects and improved the drug only in anticipation of a massive [[multi-drug-resistant tuberculosis]] outbreak.
Justin travels the world, often under assumed identities, to reconstruct the circumstances leading to Tessa's murder. As he begins to piece together Tessa's final report on the fraudulent drug tests, he learns that the roots of the conspiracy stretch further than he could have imagined; to a German pharmawatch NGO, an African aid station, and, most disturbingly to him, corrupt civil servants in the British Foreign Office.
John le Carré writes in the book's afterword: "by comparison with the reality, my story [is] as tame as a holiday postcard".